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1.Title: |
Selenium Supplementation does not Decrease Thyroid Peroxidase Antibody Concentration in Children and Adolescents with Autoimmune Thyroiditis
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Authors: |
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Journal: |
TheScientificWorldJOURNAL |
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Page Range: |
990-996 |
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Date of publication: |
1/6/2010 |
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Article Type: |
Research Article |
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Handling Editor: |
Joav Merrick |
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Domains: |
Endocrinology
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Nutrition
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Child Health & Human Development
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Immunology & Inflammation
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Synopsis: |
We present unique data of selenium supplementation in children and adolescents with autoimmune thyroiditis. The effect of selenium supplementation in this autoimmune condition has not been studied in children and adolescents so far. We feel that publishing negative results is important, especially in controversial therapies. In addition, we present data on the prevalence of goiter in autoimmune thyroiditis and on levothyroxine doses needed to treat autoimmune hypothyroidism. Such data do not exist in the literature so far. |
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2.Title: |
Statins in Neurological Disorders: Mechanisms and Therapeutic Value
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Authors: |
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Journal: |
TheScientificWorldJOURNAL |
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Page Range: |
1242-1259 |
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Date of publication: |
1/11/2009 |
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Article Type: |
Review Article |
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Handling Editor: |
Rudy Tanzi |
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Domains: |
Neuroscience
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Pharmacology
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Aging
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Neurology
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Proteins & Proteomics
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Biochemistry & Molecular Biology
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Synopsis: |
Statins, the most effective lipid-lowering drug class, reduce plasma cholesterol levels by reversibly inhibiting hepatic hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase, the rate-controlling enzyme in cholesterol synthesis. Statins have pleiotropic effects that are unrelated to their lipid-lowering capability. They are immunomodulatory agents with neuroprotective qualities that have been studied in humans, animal models, and in cell culture systems. This review explores the mechanisms through which statins exert a number of effects on brain and blood vessel function that may be beneficial in neurologic disorders such as stroke and Alzheimer's disease. |
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3.Title: |
The Effects of Different Levels of Dietary Protein and L-Carnitine on Blood Sugar and Lipids of the New GIFT Strain of Juvenile Nile Tilapia (Oreochromis niloticus)
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Authors: |
Chen, Gang ; Zhang, Minghui ; Zhang, Jiandong ; Dong, Hongbiao ; Zhou, Hui ; Tang, Baogui ; Huang, Jiansheng ; Shi, Gang ; Jiang, Ling ; Wu, Zhaohe |
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Journal: |
TheScientificWorldJOURNAL |
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Page Range: |
1197-1205 |
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Date of publication: |
1/11/2009 |
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Article Type: |
Research Article |
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Handling Editor: |
Micheal S. Allen |
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Domains: |
Freshwater Systems
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Nutrition
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Animal Sciences
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Synopsis: |
L-carnitine is a nonessential organic nutrient that is required for the entry of long-chain fatty acids into mitochondria for â oxidation. L-carnitine serves as a growth promoter, helping in the utilization of high fat levels in the diet and thus providing a protein-sparing effect. The objective of this study was to assess the effects of dietary protein and L-carnitine levels on blood sugar and lipids of juvenile new GIFT strain Nile tilapia (Oreochromis niloticus). Results from this experiment suggest that high levels of dietary protein and L-carnitine supplementation could reduce the burden of fish liver as a result of the reduction in plasma lipids. |
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4.Title: |
Hypercholesterolemia and 3-hydroxy 3-methylglutaryl Coenzyme A reductase regulation during ageing
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Authors: |
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Journal: |
TheScientificWorldJOURNAL |
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Page Range: |
564-574 |
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Date of publication: |
4/7/2009 |
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Article Type: |
Mini-Review Article |
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Handling Editor: |
Rudy Tanzi |
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Domains: |
Cell Biology
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Pharmacology
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Cardiovascular Biology
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Aging
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Metabolism & Metabolic Disease
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Biochemistry & Molecular Biology
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Synopsis: |
This paper presents a picture of the mechanisms underlying hypercholesterolemia, with particular emphasis on age-related processes. The regulation of the principal enzyme of the cholesterol biosynthetic pathway during adult life and during aging is also described. |
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5.Title: |
Metabolic Syndrome May Not be a Good Predictor of Coronary Artery Disease in the Iranian Population: Population-Specific Definitions are Required
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Authors: |
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Journal: |
TheScientificWorldJOURNAL |
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Page Range: |
86-96 |
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Date of publication: |
14/2/2009 |
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Article Type: |
Research Article |
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Handling Editor: |
Peter Little |
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Domains: |
Cardiovascular Biology
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Genes & Genomics
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Metabolism & Metabolic Disease
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Medicine
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Synopsis: |
The inability of two definitions of metabolic syndrome (MS) to predict the presence of coronary artery disease (CAD) in a non-Caucasian population was demonstrated. Angiography was used as the gold standard method for identifying patients with (cases) or without (controls) CAD. It is possible that the current definitions of MS are not appropriate for some non-Caucasian populations. |
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6.Title: |
Tissue Distribution and Depuration of the Extracted Hepatotoxic Cyanotoxin Microcystins in Crucian Carp (Carassius carassius) Intraperitoneally Injected at a Sublethal Dose
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Authors: |
Lei, Hehua ; Xie, Ping ; Chen, Jun ; Liang, Gaodao ; Yu, Ting ; Jiang, Yan |
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Journal: |
TheScientificWorldJOURNAL |
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Page Range: |
713-719 |
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Date of publication: |
31/07/2008 |
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Article Type: |
Research Article |
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Handling Editor: |
Lars Sonesten |
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Domains: |
Toxicology
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Aquatic Toxicology
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Synopsis: |
Crucian carp were injected intraperitoneally with a sub-lethal dose of extracted microcystins to examine tissue distribution and clearance of microcystins. The results are compared with our previous study in which crucian carp received a lethal dose of extracted microcystins. |
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7.Title: |
Natural Honey and Cardiovascular Risk Factors; Effects on Blood Glucose, Cholesterol, Triacylglycerole, CRP, and Body Weight Compared with Sucrose
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Authors: |
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Journal: |
TheScientificWorldJOURNAL |
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Page Range: |
463-469 |
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Date of publication: |
20/4/2008 |
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Article Type: |
Research Article |
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Handling Editor: |
Peter Little |
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Domains: |
Cardiovascular Biology
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Nutrition
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Medical Care
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Metabolism & Metabolic Disease
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Medicine
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Abstract |
It has been found that honey ameliorates cardiovascular risk factors in healthy individuals and in patients with elevated risk factors. The present study investigated the effect of natural honey on total cholesterol, low-density lipoprotein ...
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8.Title: |
Complex Regional Pain Syndrome (CRPS/RSD) and Neuropathic Pain: Role of Intravenous Bisphosphonates as Analgesics
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Authors: |
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Journal: |
TheScientificWorldJOURNAL |
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Page Range: |
229-236 |
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Date of publication: |
25/2/2008 |
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Article Type: |
Review Article |
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Handling Editor: |
George Siegel |
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Domains: |
Bone Biology
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Pharmacology
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Drug Discovery
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Neurology
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Anesthesiology
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Medicine
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Abstract |
Neuropathic pain is a sequela of dysfunction, injuries, or diseases of the peripheral and/or central nervous system pain pathways, which has historically been extremely difficult to treat. Complex regional pain syndrome (CRPS) types 1 and ...
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9.Title: |
Field and Laboratory Studies on Pathological and Biochemical Characterization of Microcystin-Induced Liver and Kidney Damage in the Phytoplanktivorous Bighead Carp
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Authors: |
Li, Li ; Xie, Ping ; Guo, Longgen ; Ke, Zhixin ; Zhou, Qiong ; Liu, Yaqin ; Qiu, Tong |
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Journal: |
TheScientificWorldJOURNAL |
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Page Range: |
121-137 |
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Date of publication: |
6/2/2008 |
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Article Type: |
Research Article |
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Domains: |
Freshwater Systems
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Pathology
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Microscopy
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Aquatic Toxicology
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Abstract |
Field and experimental studies were conducted to investigate pathological characterizations and biochemical responses in the liver and kidney of the phytoplanktivorous bighead carp after intraperitoneal (i.p.) administration of microcystins ...
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10.Title: |
Construction of Efficacious Gait and Upper Limb Functional Interventions Based on Brain Plasticity Evidence and Model-Based Measures For Stroke Patients
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Authors: |
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Journal: |
TheScientificWorldJOURNAL |
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Page Range: |
2031-2045 |
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Date of publication: |
20/12/2007 |
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Article Type: |
Discussion Paper |
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Handling Editor: |
Robert B. Daroff |
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Domains: |
Neuroscience
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Higher Level Brain Function
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Neurology
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Learning & Memory
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Motor Processes
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![[Full Text PDF]](../images/pdf.gif "Download Full Text PDF")
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Synopsis: |
There is little existing conclusive evidence upon which to base gait training and upper limb rehabilitation after stroke. Gait training and upper limb functional training studies were conducted, according to models based on sound theoretical principles and research findings. These models supported the notion that combination interventions should be provided that accurately target the array of problems underlying functional deficits. The research results indicated that both clinically significant and statistically significant functional gains can be produced in response to interventions that are accurately targeted, properly framed, and credibly measured. The patient milestones that were achieved provided evidence that the results of the neurorehabilitation were meaningful and had an impact on quality of life. |
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